Q:Computing Tissue Density from CAT Scan Images 
Author Message
 Q:Computing Tissue Density from CAT Scan Images

I'm trying to estimate the mass center of the head in 3-D and the head
moment of inertia in 3-D from CAT scan images. To do this, I need a way
of relating the CAT scan image intensity (grey levels) to the actual
tissue density (e.g.
g/cm^3)

(1) How do you do this?

(2) What software is avaliable for doing what I just described in the
    preceding paragraph?

(3) What is a Haumsfeld unit (spelling uncertain) and how does it
relate to
    CAT scan image intensity and tissue density?

Thank you very much for your help

Steve Lutes
Center for Balance Disorders Rm. NA315
Dept of Oto
Baylor College of Medicine
One Baylor Plaza
Houston, TX 77030
Voice: 713-798-6336
Fax: 713-798-8658

Check out GeometryID, a package for
linear or nonlinear system identification at:
http://www.***.com/



Tue, 16 Jan 2001 03:00:00 GMT
 Q:Computing Tissue Density from CAT Scan Images

Quote:

> I'm trying to estimate the mass center of the head in 3-D and the head
> moment of inertia in 3-D from CAT scan images. To do this, I need a way
> of relating the CAT scan image intensity (grey levels) to the actual
> tissue density (e.g.
> g/cm^3)

> (1) How do you do this?

> (2) What software is avaliable for doing what I just described in the
>     preceding paragraph?

> (3) What is a Haumsfeld unit (spelling uncertain) and how does it
> relate to
>     CAT scan image intensity and tissue density?

> Thank you very much for your help

> Steve Lutes
> Center for Balance Disorders Rm. NA315
> Dept of Oto
> Baylor College of Medicine
> One Baylor Plaza
> Houston, TX 77030
> Voice: 713-798-6336
> Fax: 713-798-8658

> Check out GeometryID, a package for
> linear or nonlinear system identification at:
> http://www.bcm.tmc.edu/cfbd/geometryID/

Here is my approach for solving this problem.  

First of all you do not need know the density of the tissue
for any given gray scale level.  Therefore you do not need to know
anything about Hounsfield units or etc.  Let's assume you have 8 bit
gray scale from 0 to 255.  Typically you will get larger dynamic
range but let's make it simple for the time being.  Divide the
spectrum into subranges which may correspond to some specific tissue
types.  For example

 40- 80  range fat,                           call this =>  density=1
 81-125  range soft tissue,                   call this =>  density=2
126-180  range bone,                          call this =>  density=3
181-225  range dense bone,                    call this =>  density=4
226-255  range metallic implant in the skull  call this =>  density=5

I am sure medical people will come up with a better division than mine.
Now stack your CT slices on top of each other to form a 3D collection
of cubes and by using density values in 2D  (I assumed that patient
did not move his head at all), determine a density
value for each cube [d(x,y,z)].  Then use the equations for center of
mass and
compute the x,y,z giving you the center coordinates. Since your data is
not continous but discrete, you need to resort to summations instead of
integrations.  d(x,y,z) is going to give you a discrete value for each
cube
and it is very convenient for summation. Because you have the density
values
of tissues d(x,y,z) both in numerator and denaminator of the equations,
actual
numbers are not important as long as you can distinguish tissue types
from
each other.  Densities will be cancelling each other in any condition.

In any approach, you will be introducing systematic errors.  Therefore,
I would not recommend going into pains for trying to come up with a
very accurate representation of tissue density values, center
coordinates.

Good Luck!
--

Feyzi INANC

Iowa State University,  Center for Nondestructive Evaluation
Applied Sciences Complex II, 1915 Scholl Road, Ames IA 50011

Ph.     (515) 294 9738          Fax.    (515) 294 6368

http://www.cnde.iastate.edu



Tue, 16 Jan 2001 03:00:00 GMT
 Q:Computing Tissue Density from CAT Scan Images


Quote:

>I'm trying to estimate the mass center of the head in 3-D and the head
>moment of inertia in 3-D from CAT scan images. To do this, I need a way
>of relating the CAT scan image intensity (grey levels) to the actual
>tissue density (e.g.
>g/cm^3)
>(3) What is a Haumsfeld unit (spelling uncertain) and how does it
>relate to
>    CAT scan image intensity and tissue density?

The Hounsfield  number (also CT number) of a pixel is defined as:

CT number=K(mu_p-mu_W)/mu_w

K=constant, if K=1000 the CT number is called Hounsfield number (HN)
mu_p= linear attenuation coefficient of the pixel
mu_w= linear attenuation coefficient of water

The linear attenuation coefficient "mu" of a matter is defined with the
following equation:
"The probability for a photon to pass through an absorber (matter, e.g.
tissue) of thickness x without interacting with the matter is: e^-mu*x"
e=the natural exponential function

mu depends on the density as well as the atom number of the matter and on
the energy of the x-rays.

Thus, ideally we have:
HN_air=-K
HN_water=0

sincerely
Jonas
______________________________________________________
Jonas Svensson, M.Sc.
Department of radiation physics
Universitetssjukhuset MAS
SE-205 02 Malm?, Sweden
Tel. +46 40 332501, Fax. +46 40 963185



Thu, 18 Jan 2001 03:00:00 GMT
 
 [ 3 post ] 

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