physical dependence vs. emotional dependence
Here are SOME of the references I promised. (An easy one, inasmuch as
Science had a special segment on {*filter*}ion in this issue of vol. 278;
I've chosen 3 most likely to be useful in this discussion)
All are in Science, 1997, 278, (5335) (3 Oct. 1997).
Leshner, AI. 45-47
Koob, GF & LeMoal, M. 52-58.
Nestler, EJ & Aghajanian, GK. 58-63.
F. LeFever
Quote:
Frank LeFever) writes:
>If I were at work just now, I could give you some references to
>excellent review articles (Science vol. 278??) to flesh-out Edward's
>assertion. We have been rather slow to explore emotional/motivational
>circuitry as systematically as we have (e.g.) visual circuitry, but we
>are getting there; and alteration of this circuitry, in a
>physiologically identifiable way (neurotransmitter receptor changes,
>gene changes, etc.) is a demonstrable consequence of frequently
>repeated drug use.
>Maybe I'll remember to make a note of the citations tomorrow...
>F. Frank LeFever, Ph.D.
>New York Neuropsychology Group
>Edward's message:
>>For those of us who are neuroscientists, there is no difference
>between
>>the two!! Emotional dependence would be expressed as changes in
>emotions
>>due to changes in underlying neurobiology--the same as physical
>dependence!
>>fn: Edward Justin Modestino, A.L.B.
>>n: Modestino, A.L.B.;Edward Justin
>>org: University of Pennsylvania
>>adr: University of Pennsylvania/Mayer Hall;;#0603; 3817
>Spruce St.;Philadelphia;PA;19104-6101;U.S.A.
>>title: M.Phil. candidate in psychobiology
>>tel;home: 215-417-7547
