my buprenorphine experience (so far) 
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 my buprenorphine experience (so far)

I think some people had expressed interest in this, so I just wanted to let you
guys know that I started taking Buprenex (for depression/anxiety) yesterday.
The only particularly bothersome side effect has been really intense itching -
I talked to my doctor and he said he would look into whether the "non-drowsy"
antihistamines are okay to use with it (if anyone has any thoughts on this I'd
be glad to hear them).

Interestingly enough, it seems to have had immediate effects on my anxiety and
motivation. The anxiety part isn't too surprising, but I'd be interested if
anyone has any rationalizations for why I feel so much more *interested* in
things than I did just 2 days ago. (I actually got some work done, even! :-P)
It's almost the sort of thing you might expect a stimulant to do.

I won't know for a while whether it's going to help with the depression thing
(been rapid-cycling at 2-3 week intervals between mild-to-moderate depression
and almost-normal) but I'm keeping a mood monitor.

-elizabeth



Sat, 18 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)
: I think some people had expressed interest in this, so I just wanted to let you
: guys know that I started taking Buprenex (for depression/anxiety) yesterday.
: The only particularly bothersome side effect has been really intense itching -
: I talked to my doctor and he said he would look into whether the "non-drowsy"
: antihistamines are okay to use with it (if anyone has any thoughts on this I'd
: be glad to hear them).

: Interestingly enough, it seems to have had immediate effects on my anxiety and
: motivation. The anxiety part isn't too surprising, but I'd be interested if
: anyone has any rationalizations for why I feel so much more *interested* in
: things than I did just 2 days ago. (I actually got some work done, even! :-P)
: It's almost the sort of thing you might expect a stimulant to do.

        I've just recently had the same experiences with Klonopin. (Minus the
itching.)  It's great to be free of anxiety w/o the frequent dosing that i was
having to do with Xanax.

-ECV



Sun, 19 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)

Quote:

>I've just recently had the same experiences with Klonopin. (Minus the
>itching.)  It's great to be free of anxiety w/o the frequent dosing that i
>was having to do with Xanax.

Klonopin helps you with anhedonia? Now that's something I wouldn't have
expected.

Frequent dosing is a problem; I'm finding buprenorphine to be a bit of a roller
coaster. Most of the side effects (dizziness, light-headedness) have been
decreasing since I first started it, though, which makes it easier. I got
Claritin for the itching and it seems to be working fairly well.

-elizabeth



Mon, 20 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)

:>I've just recently had the same experiences with Klonopin. (Minus the
:>itching.)  It's great to be free of anxiety w/o the frequent dosing that i
:>was having to do with Xanax.

: Klonopin helps you with anhedonia? Now that's something I wouldn't have
: expected.

        What kind of anhedonia are we talking about here?

-ECV



Wed, 22 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)

Quote:

>: Klonopin helps you with anhedonia? Now that's something I wouldn't have
>: expected.

>    What kind of anhedonia are we talking about here?

Anhedonia. You know, inability to enjoy things that were previously enjoyed
(and more loosly, loss of interest in life). It went away *completely* for me
as soon as I started buprenorphine; that was the most glaring change.

-elizabeth



Wed, 22 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)

:>: Klonopin helps you with anhedonia? Now that's something I wouldn't have
:>: expected.
:>
:>   What kind of anhedonia are we talking about here?

: Anhedonia. You know, inability to enjoy things that were previously enjoyed
: (and more loosly, loss of interest in life). It went away *completely* for me
: as soon as I started buprenorphine; that was the most glaring change.

        i was thihnking along the lines of {*filter*}ic anhedonia, a common side effect
of the SSRIs.

-ECV



Fri, 24 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)

Quote:

>i was thihnking along the lines of {*filter*}ic anhedonia, a common side effect
>of the SSRIs.

Eew!

(I've never heard that called anhedonia - an{*filter*}ia is the word I've heard.
Loss of libido/desire might be related to anhedonia, though, if it's part of a
cluster of things one has lost interest in.)

Well anyway, for whatever this is worth, buprenorphine doesn't seem to cause
any of those pesky {*filter*} problems (except possibly drying of mucous
membranes).

-elizabeth



Fri, 24 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)

:>i was thihnking along the lines of {*filter*}ic anhedonia, a common side effect
:>of the SSRIs.

: Eew!

: (I've never heard that called anhedonia - an{*filter*}ia is the word I've heard.
: Loss of libido/desire might be related to anhedonia, though, if it's part of a
: cluster of things one has lost interest in.)

        No. Open your Kaplan and Sadock's. (I use the K&S Study Guide; see page
135.)
        You're not getting what i'm saying. (Or, rather, i'm not being clear
enuf. <G>)
        "{*filter*}ic anhedonia" is when the strength of the {*filter*} is a "weakened", therefore,
it's not as pleasurable as possible, and the person has technically _reached_
"{*filter*}", but has not achieved relief (eg.release of tension, etc.).
        {*filter*}ic anhedonia is an {*filter*} with a "sputter" rather than being the
earth-shaking experience is should be.
        Dys{*filter*}ia/an{*filter*}ia is a different animal.

HTH,

em
:)



Sat, 25 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)
What is buprenorphine anyway? An opiate agonist, antagonist, or mixed
agonist-antagonist?

-ECV



Sun, 26 Aug 2001 03:00:00 GMT
 my buprenorphine experience (so far)
I'd never heard that one used before, but I meant anhedonia in the normal
sense, with no modifiers. (You know, the type that is a symptom of
depression...not the type that is a side effect of antidepressants.)

Buprenorphine is a partial agonist at mu receptors and an antagonist at kappa
receptors.

-elizabeth



Wed, 29 Aug 2001 03:00:00 GMT
 
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