Compounding : 3% Progesterone Gel/Cream 
Author Message
 Compounding : 3% Progesterone Gel/Cream

The reason I am writing is to find out if anyone has any advice on
compounding a 3% Progesterone Transdermal Cream or Gel/  The Doctor
prescribing this really has no idea as to how to go about compounding it.
I have exhausted all my references.   The only idea I have is a simple one.

Mixing Progesterone (micronized) into a PLO Gel mixture.  Being 3% I was
thinking that 3 gm per 100 gm (PLO).  Correct?   Now I would add a small
amount of Isopropyl {*filter*} (70%) to partially dissolve the Progesterone
 or to at least make it into a paste).   Then add the PLO components.

Any information would be helpful.   Thanks

--
Troy Lohnes, B.Sc. Pharmacy
Pharmacist Manager
Higa's Rexall Drug Store
Pincher, Creek, Alberta  T0K 1W0
(403)-627-3195



Thu, 06 Dec 2001 03:00:00 GMT
 Compounding : 3% Progesterone Gel/Cream
There's really no need to go to the trouble of using PLO. Progesterone is
very well absorbed without the use of inhancement by PLO. Incorporate the
progesterone (3% would be 3g of active and qs to 100g with cream)
into an emollient cream. You can use something as simple as Fougera's
hydrophyllic ointment (add a little preserved water to loosen it up) or make
your own. By the way, most of the Rx's I fill with progesterone cream are
20% and a few 10%. I bet he or the patient got that strength from Dr. John
R. Lee's book about menopause.

Brad Brennan, RPh

Quote:

>The reason I am writing is to find out if anyone has any advice on
>compounding a 3% Progesterone Transdermal Cream or Gel/  The Doctor
>prescribing this really has no idea as to how to go about compounding it.
>I have exhausted all my references.   The only idea I have is a simple one.

>Mixing Progesterone (micronized) into a PLO Gel mixture.  Being 3% I was
>thinking that 3 gm per 100 gm (PLO).  Correct?   Now I would add a small
>amount of Isopropyl {*filter*} (70%) to partially dissolve the Progesterone
> or to at least make it into a paste).   Then add the PLO components.

>Any information would be helpful.   Thanks

>--
>Troy Lohnes, B.Sc. Pharmacy
>Pharmacist Manager
>Higa's Rexall Drug Store
>Pincher, Creek, Alberta  T0K 1W0
>(403)-627-3195




Fri, 07 Dec 2001 03:00:00 GMT
 Compounding : 3% Progesterone Gel/Cream


Quote:
>There's really no need to go to the trouble of using PLO. Progesterone is
>very well absorbed without the use of inhancement by PLO. Incorporate the
>progesterone (3% would be 3g of active and qs to 100g with cream)
>into an emollient cream.

ABCO Distributing in Florida sells compounding chemicals and
equipment. You can browse and order online at their Web site:

                http://www.abco-dist.com

They also carry thousands of other pharmacy supply items.

--
Zack Bass



Sun, 27 Jan 2002 03:00:00 GMT
 
 [ 3 post ] 

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