caffeine- its affect on cytochrome P450 
Author Message
 caffeine- its affect on cytochrome P450

Hi!  i am a pharmacy student researching the inducing/inhibiting affects
of caffeine on cytochrome P450.  i would greatly appreciate any tid bits
of info regarding reactions and the such.
thanks,
liz


Fri, 15 May 1998 03:00:00 GMT
 caffeine- its affect on cytochrome P450

Quote:
PHARMD99 writes:
> Hi!  i am a pharmacy student researching the inducing/inhibiting affects
> of caffeine on cytochrome P450.  i would greatly appreciate any tid bits
> of info

Try combining caffeine with grapefruit juice. Since the latter contains
a compound which also is broken down by P450(2D6), this makes up for
great combo (will enhance the effects of caffeine n-fold).

A Friendly Chemist



Sat, 16 May 1998 03:00:00 GMT
 caffeine- its affect on cytochrome P450
I don't think caffeine inhibits or induces any P-450 isoenzymes.  But
it is a substrate for one of the isoenzymes, and is used to test in
vivo the activity of this isoenzyme.  Send me a mailing home or
business address (send this info by e-mail only, since you don't
everyone on BB to have it) and I'll mail you my synopsis of isoenzyme
substrates, inhibitors, etc.   Harold (clinical
pharmacologist/pharmacokineticist)


writes:

Quote:

>PHARMD99 writes:

>> Hi!  i am a pharmacy student researching the inducing/inhibiting
affects
>> of caffeine on cytochrome P450.  i would greatly appreciate any tid
bits
>> of info

>Try combining caffeine with grapefruit juice. Since the latter
contains
>a compound which also is broken down by P450(2D6), this makes up for
>great combo (will enhance the effects of caffeine n-fold).

>A Friendly Chemist



Sun, 17 May 1998 03:00:00 GMT
 
 [ 3 post ] 

 Relevant Pages 

1. "Statin" metabolism: Cytochrome P450

2. Cytochrome P450

3. Grapefruit inactivates cytochrome P450

4. cytochrome p450 inhbitors and chirrosis

5. Cytochrome p450 system

6. "Statin" metabolism: Cytochrome P450

7. Cytochrome P450

8. Cytochrome P450

9. caffeine affects brain synapses

10. list of medications affected by ctochrome P450 enzyme 3A4 and 2C9

11. ANDROGYNOUS CAFFEINE VS CAFFEINE ALKALOID

12. Androgynous Caffeine vs Caffeine Alkaloid


 
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