is insulin resistance and hyperinsulinemia interchangeable
terms not according to:

plain bizzare this article: glucose utilization improves
with simple sugar intake...  insulin slightly decreases..

(respectable journal too)

Diabetes, May 2000 v49 i5 pA72

Effect of Cola Intake on Insulin Resistance in
Male Rats. SUNMIN PARK; MI O. K. LEE; SEO
JIN YEOM; SOO RAN CHOI; SOO BONG CHOI.

Full Text: COPYRIGHT 2000 American Diabetes Association

As the traditional Korean diet has become increasingly
westernized in recent years, the prevalence of type 2 diabetes has
increased dramatically. Increased consumption of fatty foods and
carbonated drinks may be factors in insulin resistance. The
purpose of this study was to determine the effect of long term
cola intake on insulin resistance in weaning male Sprague Dawley
rats. Thirty male litters were born from 4 female rats. The litters
were randomized into cola or water drinking groups. The rats of
the water group were freely provided with 30% fat diets and
water for 6 months, while the rats of the cola group had the same
diet with cola instead of water. Insulin action was studied by
euglycemic hyperinsulinemic clamp (12 mU insulin/kg/min) in
fasting, conscious and unstressed rats at the end of the
experimental period. The daily caloric intake was not different
between groups. The composition of diet intake was different
between the two groups: rats in the cola group consumed more
carbohydrates than rats in the water consuming group. The mean
body weight of the cola group rats was lower than those of the
control group during the experimental period from the second
week. Fasting serum glucose and insulin levels of the cola group
rats tended to be lower than those of the control group rats during
the entire experimental periods, but they were not significantly
different. Whole body glucose disposal rates were higher in the
cola group than in the control group (52.5 [+ or-] 7.7 vs. 35.0 [+
or -] 12.8 mg/kg/ minute, p=0.004). Compared to the water group,
glycogen contents and glycogen synthase activities of the
quadriceps muscle in the cola group were higher by 39.4% and
54.5%, respectively (p [is less than] 0.05). In contrast, soleus
muscle triglyceride levels were significantly higher by 31.8% in
the cola group than in the water group (p [is less than] 0.05). In
conclusion, insulin action improves with increased peripheral
glucose utilization in those rats drinking cola, which may be due to
lower body weight and higher intake of carbohydrates, even
simple sugars.

SUNMIN PARK, MI O. K. LEE, SEO JIN YEOM, SOO RAN
CHOI, SOO BONG CHOI, Asan Si, ChungNam; Chung Ju Si,
ChungBuk, Korea

Not sure why you think this is bizzare. In healthy young people with
balanced energy utilisation, carbohydrates promote efficient glucose
utilisation and insulin response. Perhaps not forever though. Still a good
case for low GI and calorie control over the longer term.

Fat, excess calories, lack of exercise and obesity cause glucose intolerance
and insulin resistance.

Hyperinsulinaemia is a quantitative term; insulin resistance is a functional
term. Not sure they are meant to be the same.

Paul R