Do mast cells die after degranulation? 
Author Message
 Do mast cells die after degranulation?

Also, what mechanisms affect their replenishment after death by


Thu, 27 Apr 2000 03:00:00 GMT
 Do mast cells die after degranulation?

(Matthew Dubuque) writes:
>Sorry, probably a dumb question, but do they?



No, they don't.

Ann M. Dvorak has done some research on mast cell recovery from degranulation.
(Cell. Immunol. 1987; 105:199-204. {*filter*} 1988; 71:76-85. Lab. Invest. 1986;
If you want to see nice pictures you should read: Ann M. Dvorak, Recovery of
human lung mast cells from anaphylactic degranulation utilizes a mixture of
conservation and synthetic mechanisms. In: Mast Cell and Basophil
Differentiation and Function in Health and Disease, edited by S.J. Galli and
K.F. Austen. Raven Press, NY, 1989.

Best regards,

Frans J. van Overveld
Dept. Respiratory Med.
Univ. Antwerp

Sun, 30 Apr 2000 03:00:00 GMT
 [ 2 post ] 

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