Lyme borreliosis in neurology and psychiatry 
Author Message
 Lyme borreliosis in neurology and psychiatry

TITLE: [Lyme borreliosis in neurology and psychiatry]
VERNACULAR TITLE: Die Lyme-Borreliose in Neurologie und Psychiatrie.
AUTHOR AFFILIATION: Neurologische Klinik mit Poliklinik, Universitat Freiburg.
SOURCE: Fortschr Med 1990 Apr 10;108(10):191-3, 197
CITATION IDS: PMID: 2187778 UI: 90256076

ABSTRACT: Neurological manifestations of Lyme disease are as multifarious as
the entire spectrum of this common infection. In stage I, fibromyalgia and,
more rarely, painful muscular fasciculation, dominate the clinical picture. In
the individual case, mild psychic abnormalities may already be observed.
Characteristic of the 2nd stage is lymphocytic meningopolyneuritis.
Involvements of the CNS are expressed not so much in focal deficits, as in
diffuse psychopathological disorders. In stage 3, CNS manifestations are
characterized by chronic, in part multifocal, encephalitides and
encephalomyelitides, isolated transverse myelitides and cerebral vasculitic
disorders. The clinical symptomatology may be dominated by severe psychiatric
syndromes. Connatal and subclinical latent infections of the nervous system
with Borrelia represent special forms.
MAIN MESH HEADINGS: Lyme Disease/*diagnosis
Mental Disorders/*diagnosis
Nervous System Diseases/*diagnosis ADDITIONAL MESH HEADINGS: Diagnosis,
English Abstract
Lyme Disease/complications
Mental Disorders/etiology
Nervous System Diseases/etiology PUBLICATION TYPES: JOURNAL ARTICLE

TITLE: Survival of Borrelia burgdorferi in antibiotically treated patients with
Lyme borreliosis.
AUTHORS: Preac-Mursic V; Weber K; Pfister HW; Wilske B; Gross B; Baumann A;
Prokop J
AUTHOR AFFILIATION: Neurologische Klinik Grosshadern, Munchen, FR Germany.
SOURCE: Infection 1989 Nov-Dec;17(6):355-9
CITATION IDS: PMID: 2613324 UI: 90129322

ABSTRACT: The persistence of Borrelia burgdorferi in patients treated with
antibiotics is described. The diagnosis of Lyme disease is based on clinical
symptoms, epidemiology and specific IgG and IgM antibody titers to B.
burgdorferi in serum. Antibiotic therapy may abrogate the antibody response to
the infection as shown in our patients. B. burgdorferi may persist as shown by
positive culture in MKP-medium; patients may have subclinical or clinical
disease without diagnostic antibody titers to B. burgdorferi. We conclude that
early stage of the disease as well as chronic Lyme disease with persistence of
B. burgdorferi after antibiotic therapy cannot be excluded when the serum is
negative for antibodies against B. burgdorferi.MAIN MESH HEADINGS:
Antibiotics/*therapeutic use
Borrelia burgdorferi/*growth & development
Lyme Disease/*drug therapy ADDITIONAL MESH HEADINGS: {*filter*}
Borrelia burgdorferi/immunology
Borrelia burgdorferi/isolation & purification
Case Report
Child, Preschool
Lyme Disease/immunology
Lyme Disease/microbiology

Sat, 05 Jan 2002 03:00:00 GMT
 [ 1 post ] 

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