New Treatments for Liver Cancer 
Author Message
 New Treatments for Liver Cancer

?
 From Seminars in Liver Disease

Local Ablation Therapy for Hepatocellular Carcinoma

Shuichi Okada, M.D., Ph.D.,

 From the Hepatobiliary and Pancreatic Oncology Division, National Cancer
Center Hospital, Tokyo, Japan.

Abstract

Several local ablation methods, most of which can be performed percutaneously
under imaging guidance, have recently been developed as minimally invasive
therapy for hepatocellular carcinoma (HCC). Among these, percutaneous ethanol
injection has been the most widely performed and is now accepted as an
attractive alter-native to surgery in patients with small HCC. Other local
ablation therapeutic options to achieve more effective tumor necrosis with
less invasiveness have also been developed. Some of these techniques, such as
microwave coagulation therapy and radiofrequency ablation, have already been
introduced clinically. However, the real role of these new ablation methods
in the treatment of HCC remains to be determined because of the lack of
randomization and the small number of patients in the published series.
Therefore, further trials, possibly randomized trials to compare the results
of different options, are mandatory. Moreover, the prevention of recurrence
after local ablation therapy for HCC has become an urgent problem to be
resolved.

[Sem Liver Disease 19(3):323-328, 1999. ? 1999 Thieme Medical Publishers,
Inc.]

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Mon, 28 Oct 2002 03:00:00 GMT
 
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