Dear all!

First of all, please accept my apologies for cross-posting. I hope you will
understand my motives.

This August my 53-year old mom was diagnosed with {*filter*} cancer and was
immediately operated. I learned about it only I went on vacation to my home
country in October - my family didn't tell me anything before. They knew I
was surviving a personal loss and they didn't want to upset me even more.

My mom is a wonderful and brave person who did so much for me and for many
other people. I was and am so depressed and scared that I haven't been able
to sleep normally for several months. Yet I know I must be strong and as my
mom is willing to fight, I want to do whatever I can to help her.

Dear all . I am asking you to share any information which might deal with
the situation my mom has.

I.        Diagnosis: {*filter*} cancer, T2M1N0, or stage IIb (I don't know why
T2, cause her tumour, according to my mom, was less than 2 cm). Nodes: out
of 10 nodes which were removed, 3 are positive. Histology: stage 2
differentiation. Hormone dependency - no information.

II.     Treatment: radical mastectomy.

1 course of chemotherapy (methotrixate on the 1st and 8th day, 14 shots of
cyclophosphane, pills of tamoxifene twice a day, methyluracil three times a
day); 1 course of radiotherapy; 2 course of chemotherapy - currently
(methotrixate, endoxan, pills of tamoxifene, methyluracil). There will be 6
overall.

Now my questions are:

1)      since we know that lymph nodes were involved, the chance of distant
metastasis increases. What can be done (except traditional methods) to
prevent their formation, or if small ones are formed, to destroy them?

2)      what alternative methods are recommended to use and if you used them
personally or know someone who did, what are the results?

3)      do you have information of using Gleevec for {*filter*} cancer
management?

4)      what is the efficiency of Herceptine?

5)      has anyone used:

- the method of general high-frequency hyperthermy (heating of the whole
body by 43 C) and what are the results? Does it make sense currently for my
mom?

- immune stimulators 714-X, esberitox,  glutoxim, cessiac and yuccalive,
proleukine;

-   Rife Machine;

-   Laetril;

-   Ukrain;

-   is there official statistics on efficiency of {*filter*} cancer treatment in
Mexico?

If you can, please advise a doctor who could give me professional advice
here in Canada or elsewhere. I live in Calgary, Alberta.

Thank you very much. I wish all of you health and God bless you!

Sincerely,

Nika

The treatment she has had/is having is designed to do this.

Don't know of any data for adjuvant use.

Don't know of any data for adjuvant use.

There is  no evidence that it would benefit your mom, and it's quite
unpleasant.

None of the above are any use.

No reliable ones.

The Tom Baker cancer instutute in Calgary is excellent. I'd suggest
discussing these issues with an oncologist there.

Geez .. I'll meet ya at Tim Hortons on twelfth avenue sw .. ;)

There is a problem more and more researchers are becoming aware
of ..
This is the heme iron from the meat we eat ..
They have shown the body controls the iron we have in it by
absorption and once a set limit is met .. the body begins to
downregulate the PERCENTAGE of iron we absorb.
It has been shown the heme iron though .. found in meat / {*filter*}
is NOT controlled and bypasses the bodies processes which would
normally not allow too much iron to be absorbed.
Laetrile .. is chock full of cyanodins which .. is cyanide in
its natural form and cyanide is an effective chelator of iron ..
binder of iron.
Below you will find a compilation of articles which speak to the
problem of iron and what  researchers / scientists are beginning
to find seem to have some good .. results.

Chelators are as we speak being funded by the NIH in order to
remove iron from disease ..

Oxidation / free radicals / rust have been closely linked to
{*filter*} cancer.

Date: Thu, 26 Jul 2001 20:49:24 -0600 (MDT)


Subject: cancer/iron

   Cancer Lett 1988 Aug 30;41(3):251-6

Dietary iron enhances the tumor rate in dimethylhydrazine-induced colon
carcinogenesis in mice.

    Siegers CP, Bumann D, Baretton G, Younes M

   Institute of Toxicology, Medical University of Lubeck, F.R.G.

   Treatment of male mice with 20 mg/kg dimethylhydrazine (DMH) s.c. for
   10 weeks caused a mean tumour rate of 3.5 after 20 weeks. Dietary iron
   (3.5% Fefumarate for 10 weeks) enhanced the mean tumour rate to 13.9.
   All tumours detected were localized exclusively in the distal colon
   and rectum. The iron load caused a 6.5-fold increase in the mucosal
   Fe-concentration in the proximal as well as distal colon.
   DMH-demethylase activity was not influenced by iron and did not differ
   between proximal and distal segments. Cytosolic {*filter*} dehydrogenase
   (ADH) activity was also not altered by iron, but was 3.3-fold higher
   in the distal colon and rectum as compared to proximal segments; this
   might explain the DMH-induced tumorigenesis in the distal colon only.
   It is suggested that iron ions might evoke cocarcinogenic activity by
   a stimulation of cell proliferation.

   PMID: 3409203, UI: 88310811
     _________________________________________________________________

   Save the above report in [Macintosh] [Text] format
   Order documents on this page through Loansome Doc
     _________________________________________________________________

                             The Cancer Stopper

   Dateline: 04/02/98

   Researchers at the University of Maryland School of Medicine have
   found a potentially potent weapon in the fight against cancer. A sugar
   phosphate, called inositol hexaphosphate (IP6), was found to be
   effective against certain types of liver cancer in mice.

   IP6 is a sugar molecule with six phosphates attached. It occurs
   naturally in nature in such diverse things as wheat, rice bran,
   legumes and even in nearly all mammal cells. It helps to regulate
   cellular functions, particularly cell differentiation and
   proliferation.

   Scientists took human liver cells that were cancerous, treated them
   with various levels of IP6, and transplanted the treated cells into
   mice. IP6 was found to "check" the growth of the cancerous cells--not
   by destroying the cancer cells but by making the cancerous cells act
   like normal, healthy cells. Inositol hexaphosphate decreases the
   proliferation of the cancer cells, keeping them in "check."

   The higher the dose of IP6, the better the results. In the tests, mice
   that had transplanted cells with higher dosages of IP6 developed
   virtually no cancer. Those that had untreated cells developed the
   tumors we would expect from diseased cells.

   Some of the mice with tumors present were then tested as a follow-up.
   Injections of IP6 were given to the mice with tumors and, over the
   course of the treatment, the tumors decreased in size, sometimes
   almost five fold less than the size of the tumor at the start of the
   treatment.

   Interestingly enough, IP6 binds with several important minerals, like
   copper and zinc. Scientists suggested that taking the "pure" form of
   the substance rather than ingesting large quantities in the diet might
   prove more beneficial in fighting cancer.

   Scientists also hope that IP6 could be used in the treatment of other
   diseases and disorders, particularly in the fight against AIDS.

   Will IP6 prove to be a potent new weapon against cancer in the future,
   or is this another in the long line of substances that haven't lived
   up to their potential?

     __________________________________________________________________

                             The Cancer Stopper

   Dateline: 04/02/98

   Researchers at the University of Maryland School of Medicine have
   found a potentially potent weapon in the fight against cancer. A sugar
   phosphate, called inositol hexaphosphate (IP6), was found to be
   effective against certain types of liver cancer in mice.

   IP6 is a sugar molecule with six phosphates attached. It occurs
   naturally in nature in such diverse things as wheat, rice bran,
   legumes and even in nearly all mammal cells. It helps to regulate
   cellular functions, particularly cell differentiation and
   proliferation.

   Scientists took human liver cells that were cancerous, treated them
   with various levels of IP6, and transplanted the treated cells into
   mice. IP6 was found to "check" the growth of the cancerous cells--not
   by destroying the cancer cells but by making the cancerous cells act
   like normal, healthy cells. Inositol hexaphosphate decreases the
   proliferation of the cancer cells, keeping them in "check."

   The higher the dose of IP6, the better the results. In the tests, mice
   that had transplanted cells with higher dosages of IP6 developed
   virtually no cancer. Those that had untreated cells developed the
   tumors we would expect from diseased cells.

   Some of the mice with tumors present were then tested as a follow-up.
   Injections of IP6 were given to the mice with tumors and, over the
   course of the treatment, the tumors decreased in size, sometimes
   almost five fold less than the size of the tumor at the start of the
   treatment.

   Interestingly enough, IP6 binds with several important minerals, like
   copper and zinc. Scientists suggested that taking the "pure" form of
   the substance rather than ingesting large quantities in the diet might
   prove more beneficial in fighting cancer.

   Scientists also hope that IP6 could be used in the treatment of other
   diseases and disorders, particularly in the fight against AIDS.

   Will IP6 prove to be a potent new weapon against cancer in the future,
   or is this another in the long line of substances that haven't lived
   up to their potential?

     __________________________________________________________________

<pre>
Subject: Ip6/phytic acid

   _________________________________________________________________

   Antitumor Activity of Physic Acid (Inositol Hexaphosphate) in Murine
          Transplanted and Metastatic Fibrosarcoma, a Pilot Study
          Authors: Vucenik I, Tomazic VJ, Fabian D, Shamsuddin AM
          Source: Cancer Letters. 1992; 65:9-13.
   _________________________________________________________________

   Comparison of Pure Inositol Hexaphosphate and High-Bran Diet in the
          Prevention of DMBA-Induced Rat Mammary Carcinogenesis
          Authors: Vucenik I, Yang G, Shamsuddin AM
          Source: Nutrition and Cancer. 1997; 28(1):7-13.
   _________________________________________________________________

   Dose-dependent Inhibition of Large Intestinal Cancer by Inositol
          Hexaphosphate in F344 Rats
          Authors: Ullah A, Shamsuddin AM
          Source: Carcinogenesis. 1990; 2(12):2219-2222.
   _________________________________________________________________

   Effects of Inositol Hexaphosphate on Growth and Differentiation in
          K-562 Erythroleukemia Cell Line
          Authors: Shamsuddin AM, Baten A, Lalwani ND
          Source: Cancer Letters. 1992; 64:195-202.
   _________________________________________________________________

   Growth Inhibition and Differentiation of HT-29 Cells in vitro by
          Inositol Hexaphosphate (Phytic Acid)
          Authors: Sakamoto K, Venkatraman G, Shamsuddin AM
          Source: Carcinogenesis. 1993; l4(9):l815-1819.
   _________________________________________________________________

   IP6-Induced Growth Inhibition and Differentiation of HT-29 Human Colon
          Cancer Cells: Involvement of Intracellular Inositol Phosphates
          Authors: Yang G, Shamsuddin AM
          Source: Anticancer Research. 1995; 15:2479-2488.
   _________________________________________________________________

   IP6: A Novel Anti-Cancer Agent
          Authors: Shamsuddin AM, Vucenik I, Cole KE
          Source: Life Sciences. 1997; 61(4):343-354.
   _________________________________________________________________

   Inhibition of Rat Mammary Carcinogenesis by Inositol Hexaphosphate
          (Phytic Acid). A Pilot Study.
          Authors: Vucenik I, Sakamoto K, Bansal M, Shamsuddin AM
          Source: Cancer Letters.1993; 75:95-102.
   _________________________________________________________________

   Inositol Hexaphosphate Inhibits Cell Transformation and Activator
          Protein 1 Activation by Targeting Phosphatidylinositol-3'
          Kinase
...

read more »

for> my > > mom?

unpleasant.

Could you please expand on that a bit more? I have evidence that it benefits
patients with IV stage of cancer of various localization and I talked in
person to one such patient. What do you mean unpleasant? This is not
something like putting a patient in hot water. They do it only in one place
in Russia (I mean this technology) on special equipment under general
anaesthesia. Special devices control brain, lungs, etc and {*filter*} is heated
separately. Yes, there are risks (weak heart, lung problems, old age).

I am asking the question about this method, cause I thought people might
have used it abroad or someone personally experienced it.>

Could you please comment on glutoxim? again it is a new drug, and it has
been referred to as a powerful stuff by some people - they are reporting
significant improvement. Is there any practical evidence it is not
efficient?

discussing these issues with an oncologist there.

Thank you for this! I will definitely contact a professional there. Can you
refer someone in particular?

Sincerely,

Nika

 >Geez .. I'll meet ya at Tim Hortons on twelfth avenue sw .. ;)

The world is really small :) I am on the 14thAv :)
 I will study the materials that you posted - thank you very much and maybe
we'll meet some day?

I have heard of trials being done on copper chelators (not iron!) as
some copper-dependent pathways appear to be involved in various
angiogenic processes.

There is apparently some toxicity to manage so it is not all that simple.

btw this is from biotech investing research; I am NOT a medical professional.

It is always .. considerate .. if you can include an article or
two to help the person along ..

Who loves ya.
Tom
--
Jesus was a Vegetarian! http://www.nucleus.com/watchman
Moses was a Mystic! http://www.nucleus.com/watchman/light.html

What evidence? Don't confuse anecdote and enthusiasm with evidence.

Anaesthetics aren't very pleasant in my view.

Don't know it, Im afraid.

Just ask for a consultation with one of the oncologists who specialises in
the particular cancer of concern.

Nika, you are playing with fire.

If you look at our FAQ website at www.cancersupporters.com/ascb you will
find a report on one of our contributors' experiences regarding alternative
treatments in Mexico.

If distant metastases occur, there is no such thing as a few small ones.
Metastatic cancer has to be viewed as a systemic disease, and surgery is
rarely helpful.  If you find any distant mets., you know there are a load
around you haven't found (yet).

Herceptin is significantly effective in delaying metastatic cancers which
express significant amounts of the appropriate protein.  It also has heart
toxicity issues and is not approved for use in earlier stages.

Please do whatever you must in order to sleep normally.  You can't help
anyone else if you don't first look after yourself.  Believe me, I know, I
got the t-shirt.

Tim Jackson