Quote:
> here in Canada or elsewhere. I live in Calgary, Alberta.
Geez .. I'll meet ya at Tim Hortons on twelfth avenue sw .. ;)
There is a problem more and more researchers are becoming aware
of ..
This is the heme iron from the meat we eat ..
They have shown the body controls the iron we have in it by
absorption and once a set limit is met .. the body begins to
downregulate the PERCENTAGE of iron we absorb.
It has been shown the heme iron though .. found in meat / {*filter*}
is NOT controlled and bypasses the bodies processes which would
normally not allow too much iron to be absorbed.
Laetrile .. is chock full of cyanodins which .. is cyanide in
its natural form and cyanide is an effective chelator of iron ..
binder of iron.
Below you will find a compilation of articles which speak to the
problem of iron and what researchers / scientists are beginning
to find seem to have some good .. results.
Chelators are as we speak being funded by the NIH in order to
remove iron from disease ..
Oxidation / free radicals / rust have been closely linked to
{*filter*} cancer.
Date: Thu, 26 Jul 2001 20:49:24 -0600 (MDT)
Subject: cancer/iron
Cancer Lett 1988 Aug 30;41(3):251-6
Dietary iron enhances the tumor rate in dimethylhydrazine-induced colon
carcinogenesis in mice.
Siegers CP, Bumann D, Baretton G, Younes M
Institute of Toxicology, Medical University of Lubeck, F.R.G.
Treatment of male mice with 20 mg/kg dimethylhydrazine (DMH) s.c. for
10 weeks caused a mean tumour rate of 3.5 after 20 weeks. Dietary iron
(3.5% Fefumarate for 10 weeks) enhanced the mean tumour rate to 13.9.
All tumours detected were localized exclusively in the distal colon
and rectum. The iron load caused a 6.5-fold increase in the mucosal
Fe-concentration in the proximal as well as distal colon.
DMH-demethylase activity was not influenced by iron and did not differ
between proximal and distal segments. Cytosolic {*filter*} dehydrogenase
(ADH) activity was also not altered by iron, but was 3.3-fold higher
in the distal colon and rectum as compared to proximal segments; this
might explain the DMH-induced tumorigenesis in the distal colon only.
It is suggested that iron ions might evoke cocarcinogenic activity by
a stimulation of cell proliferation.
PMID: 3409203, UI: 88310811
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_________________________________________________________________
The Cancer Stopper
Dateline: 04/02/98
Researchers at the University of Maryland School of Medicine have
found a potentially potent weapon in the fight against cancer. A sugar
phosphate, called inositol hexaphosphate (IP6), was found to be
effective against certain types of liver cancer in mice.
IP6 is a sugar molecule with six phosphates attached. It occurs
naturally in nature in such diverse things as wheat, rice bran,
legumes and even in nearly all mammal cells. It helps to regulate
cellular functions, particularly cell differentiation and
proliferation.
Scientists took human liver cells that were cancerous, treated them
with various levels of IP6, and transplanted the treated cells into
mice. IP6 was found to "check" the growth of the cancerous cells--not
by destroying the cancer cells but by making the cancerous cells act
like normal, healthy cells. Inositol hexaphosphate decreases the
proliferation of the cancer cells, keeping them in "check."
The higher the dose of IP6, the better the results. In the tests, mice
that had transplanted cells with higher dosages of IP6 developed
virtually no cancer. Those that had untreated cells developed the
tumors we would expect from diseased cells.
Some of the mice with tumors present were then tested as a follow-up.
Injections of IP6 were given to the mice with tumors and, over the
course of the treatment, the tumors decreased in size, sometimes
almost five fold less than the size of the tumor at the start of the
treatment.
Interestingly enough, IP6 binds with several important minerals, like
copper and zinc. Scientists suggested that taking the "pure" form of
the substance rather than ingesting large quantities in the diet might
prove more beneficial in fighting cancer.
Scientists also hope that IP6 could be used in the treatment of other
diseases and disorders, particularly in the fight against AIDS.
Will IP6 prove to be a potent new weapon against cancer in the future,
or is this another in the long line of substances that haven't lived
up to their potential?
__________________________________________________________________
The Cancer Stopper
Dateline: 04/02/98
Researchers at the University of Maryland School of Medicine have
found a potentially potent weapon in the fight against cancer. A sugar
phosphate, called inositol hexaphosphate (IP6), was found to be
effective against certain types of liver cancer in mice.
IP6 is a sugar molecule with six phosphates attached. It occurs
naturally in nature in such diverse things as wheat, rice bran,
legumes and even in nearly all mammal cells. It helps to regulate
cellular functions, particularly cell differentiation and
proliferation.
Scientists took human liver cells that were cancerous, treated them
with various levels of IP6, and transplanted the treated cells into
mice. IP6 was found to "check" the growth of the cancerous cells--not
by destroying the cancer cells but by making the cancerous cells act
like normal, healthy cells. Inositol hexaphosphate decreases the
proliferation of the cancer cells, keeping them in "check."
The higher the dose of IP6, the better the results. In the tests, mice
that had transplanted cells with higher dosages of IP6 developed
virtually no cancer. Those that had untreated cells developed the
tumors we would expect from diseased cells.
Some of the mice with tumors present were then tested as a follow-up.
Injections of IP6 were given to the mice with tumors and, over the
course of the treatment, the tumors decreased in size, sometimes
almost five fold less than the size of the tumor at the start of the
treatment.
Interestingly enough, IP6 binds with several important minerals, like
copper and zinc. Scientists suggested that taking the "pure" form of
the substance rather than ingesting large quantities in the diet might
prove more beneficial in fighting cancer.
Scientists also hope that IP6 could be used in the treatment of other
diseases and disorders, particularly in the fight against AIDS.
Will IP6 prove to be a potent new weapon against cancer in the future,
or is this another in the long line of substances that haven't lived
up to their potential?
__________________________________________________________________
<pre>
Subject: Ip6/phytic acid
_________________________________________________________________
Antitumor Activity of Physic Acid (Inositol Hexaphosphate) in Murine
Transplanted and Metastatic Fibrosarcoma, a Pilot Study
Authors: Vucenik I, Tomazic VJ, Fabian D, Shamsuddin AM
Source: Cancer Letters. 1992; 65:9-13.
_________________________________________________________________
Comparison of Pure Inositol Hexaphosphate and High-Bran Diet in the
Prevention of DMBA-Induced Rat Mammary Carcinogenesis
Authors: Vucenik I, Yang G, Shamsuddin AM
Source: Nutrition and Cancer. 1997; 28(1):7-13.
_________________________________________________________________
Dose-dependent Inhibition of Large Intestinal Cancer by Inositol
Hexaphosphate in F344 Rats
Authors: Ullah A, Shamsuddin AM
Source: Carcinogenesis. 1990; 2(12):2219-2222.
_________________________________________________________________
Effects of Inositol Hexaphosphate on Growth and Differentiation in
K-562 Erythroleukemia Cell Line
Authors: Shamsuddin AM, Baten A, Lalwani ND
Source: Cancer Letters. 1992; 64:195-202.
_________________________________________________________________
Growth Inhibition and Differentiation of HT-29 Cells in vitro by
Inositol Hexaphosphate (Phytic Acid)
Authors: Sakamoto K, Venkatraman G, Shamsuddin AM
Source: Carcinogenesis. 1993; l4(9):l815-1819.
_________________________________________________________________
IP6-Induced Growth Inhibition and Differentiation of HT-29 Human Colon
Cancer Cells: Involvement of Intracellular Inositol Phosphates
Authors: Yang G, Shamsuddin AM
Source: Anticancer Research. 1995; 15:2479-2488.
_________________________________________________________________
IP6: A Novel Anti-Cancer Agent
Authors: Shamsuddin AM, Vucenik I, Cole KE
Source: Life Sciences. 1997; 61(4):343-354.
_________________________________________________________________
Inhibition of Rat Mammary Carcinogenesis by Inositol Hexaphosphate
(Phytic Acid). A Pilot Study.
Authors: Vucenik I, Sakamoto K, Bansal M, Shamsuddin AM
Source: Cancer Letters.1993; 75:95-102.
_________________________________________________________________
Inositol Hexaphosphate Inhibits Cell Transformation and Activator
Protein 1 Activation by Targeting Phosphatidylinositol-3'
Kinase
...
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