Treatment for Myelodysplasia (Refractory Anaemia) 
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 Treatment for Myelodysplasia (Refractory Anaemia)

My father has been diagnosed with myelodysplasia (refractory anaemia - RA).
He is 75 and has no symptoms except for a low and falling haemoglobin count.
He is now due for his second {*filter*} transfusion.  (First time round he was
down to 7.4).  A course of Prendisolone (corticosteroid) has been judged
ineffective.  The specialists say that Epoetin (Erythropoetin) would not be
appropriate for patients with dysfunctional bone marrow.  They are
considering cyclosporin - another immunosuppressant.

Can anybody advise the latest thinking on medication as we believe that so
far my father has only been given palliatives.

Thanks in advance  Victor



Tue, 29 Jan 2002 03:00:00 GMT
 Treatment for Myelodysplasia (Refractory Anaemia)
On Fri, 13 Aug 1999 17:32:52 +0100, "Victor A Hill"

Quote:

>My father has been diagnosed with myelodysplasia (refractory anaemia - RA).
>He is 75 and has no symptoms except for a low and falling haemoglobin count.
>He is now due for his second {*filter*} transfusion.  (First time round he was
>down to 7.4).  A course of Prendisolone (corticosteroid) has been judged
>ineffective.  The specialists say that Epoetin (Erythropoetin) would not be
>appropriate for patients with dysfunctional bone marrow.  They are
>considering cyclosporin - another immunosuppressant.

>Can anybody advise the latest thinking on medication as we believe that so
>far my father has only been given palliatives.

>Thanks in advance  Victor


Erythopoetin is worth a try, even with the dysfunctional marrow.
Generally, it takes higher doses than in other situations.  I also
have used Vitamin B-6 and testosterone tablets in an attempt to reduce
transfusional requirements.  H2


Wed, 30 Jan 2002 03:00:00 GMT
 
 [ 2 post ] 

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