
Do Hypertension Treatment Guidelines Need Revision?
See the recent thread "Flowmax" on this NG. This was my experience after six
days of Flowmax.
Quote:
> I am about to start Proscar and Flomax. As I already take two BP meds I
> voiced my concern to the doc about the additional effect on my BP. He
> suggested that I take them at bed time to begin with, as Flowmax is slow
> release I doubt if it will make much difference when taken.
> Derek.
After starting Flowmax and Proscar last Tuesday my BP was lower than usual
the next morning and eventually went as low as 106/58 but my normally drug
induced pulse rate of under 50 was up to 61. By evening the headache began
and by Sunday my BP was much higher than normal all day. I woke up early
Monday morning with my heart pounding and checked my BP and pulse getting a
reading of 214/85 and a pulse of 112. Alarmed my wife phoned the docter who
came round to check me out. He said that my BP was still as high but heart
sounded all right and that my pulse had gone to 90. He had never heard of
such a reaction before but to stop taking the medication.
I did a Google search and found others who had a similar problem with Alpha
Blockers:-
"I have had bph problems for quite a while now. I have tried Cordura
and it really made me dizzy. I have tried Hytrin which I may have to
go back too. I was only taking 2 mgs a day, but it was helping a little.
The problem was it was making my heart beat pretty rapidlyt at times
and I decided to discontinue it".
Also:-
"A few days ago, I read an article in "Worst Pills, Best Pills" newsletter
warning of the dangers of alpha-blocker {*filter*}. The article, by Sidney Wolfe,
M.D., cautioned that these {*filter*} can significantly increase the chance of
heart attack or stroke. The article specifically named Cardura, Hytrin and
Flomax, all of which belong to the alpha-blocker family. Although, I had
been taking Flomax for the last two years and Proscar for more than five
years, I reluctantly decided to discontinue the Flomax out of concern that I
might increase my risk of stroke"
Also:-----
" I was having dizzy spells, weakness and after very little exertion, my
pulse rate would go sky
high. I normally have low {*filter*} pressure and that might have been some of
the problem. The fact that there are increased cases of congestive heart
failure and stroke are enough to make you think twice or more about taking
it".
When I posted my problem on a cardiac NG I got this reply from a Doctor:-
" I would wonder about the Flomax interacting with the verapamil by
lowering levels of the latter. This would raise both your heart rate
and your BP"
Derek.
Quote:
> I have read summaries of a couple of recent studies (since 2000)
> indicating that "normal" and "high normal" {*filter*} pressure per AHA
> guidelines can result in target organ damage.
> How rigorous and well-accepted are these studies?
> Do the AHA guidelines need revision, and is this likely in the near
> future?
> I have until recently been in the "high normal" range even with
> treatment from a board-cert. cardiologist for decades. I was only
> taking 5 mg Altace. He seemed satisfied with this since various tests
> including cardiac ultrasound remained normal. At present I am in the
> "optimal" range since increasing Altace to 10 mg following recent BP
> increases into the hypertensive range.
> Given these recent studies, I'm now troubled that my treatment was not
> more aggressive all along, but I trusted his expertise and judgement.
> He seemed more concerned about my diet, exercise, healthy lifestyle,
> and absence of medication side effects, over BP reduction into the
> optimal range.
> I only recall one physician during a brief exam about 20 years ago
> telling me that high normal was not good, and that I shouldn't be
> satisfied with high normal. All others I saw for various unrelated
> reasons seemed unconcerned.
> Is the community at large lagging the best science? Thanks.