Strange Clonidine side effects
Wayne, thank you for your response. OK, I am a bit confused. I thought the
sympathetic nervous sytem was the "poop and run" (like fear causing one to
mess their pants), and the parasympathetic system was "eat, relax, and
absorb." which slows down the GI tract to absorb food. Wayne, I have found
a lot of information on how the sympathtetic and parasympathetic system
affects smooth muscle. What about striated muscle (i.e. muscle tension)?
Thank you for your information--it is very valuable to me, and I appreciate
it very much!
Thanks,
Mike
--
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Quote:
> > I didn't find clonidine relaxing at all when I was on it. The clonidine
> > might not be entirely to blame though. Perhaps it's the combination with
> > labetolol that's the problem.
> > Pierre
> > "Mike [remove (SPAM_BLOCKER) from my email address to reply]"
> > > I have been titrating Clonidine upwards to currently .1 mg/day (a low
> > dose,
> > > but I am working to get up to a dose that would let me utilize the
> patch).
> > > This is being used to treat an autonomic nervous system disease
> (postural
> > > orthostatic tachycardia syndrome) which is affecting my circulation.
> > Since
> > > I also tend to get hyperadrenergic severe hypertensive burts, this is
> > being
> > > added to my small dose of laebetalol to try and prevent that from
> > happening.
> > > I expected it to be relaxing, but instead the opposite has occured:
> > > My muscles are very tight, incuding severe tension headaches
> > > I get shakey and sometimes chills (this I got before clonidine because
> of
> > > some autonomic nervous system problems--but now it is worse)
> > > Increased GI motility (loose stools and diahrrea)
> > > These side effects seem to be the opposite of what one would expect
from
> > > clonidine. It feels like my already hyperactive sympathetic nervous
> sytem
> > > is being accelerated instead of decelerated. It is like my body is
> upset
> > > that I am trying to lower {*filter*} pressure and heart rate and is trying
to
> > > override clonidine's effects. I was looking forward to a nice
> > > parasympathetic relaxation, but instead I am bouncing off the walls.
> This
> > > sucks. I am not sure what to do. Will this get better? Should I
just
> > ride
> > > it out?
> > > Any input or experiences would be greatly appreciated.
> > > Thanks,
> > > Mike
> > > --
> > > To reply via email remove the (SPAM_BLOCKER) from my email address:
> > YOU will decrease the tone of the autonomic nervous system. Via the
> nucleus tractus solitarus, thus inhibiting outflow from the vasomotor
> center. decreasing adrenergic tone can stimulate the gi tract. remember
> increasing autonomic tone in the fight or flight syndrome shuts down the
gi
> tract. We are talking the adrenergic nervous system here. Remember,
> stimulating the NTS causes an inhibition in the VMC.
