Brain Res 1997 Jun 13;759(2):306-308

Effects of chronic ibogaine treatment on cerebellar Purkinje cells in the rat.
Helsley S, Dlugos CA, Pentney RJ, Rabin RA, Winter JC
Department of Pharmacology and Toxicology, School of Medicine and Biomedical
 Sciences, State
University of New York at Buffalo, 14214-3000, USA.
The present investigation assessed the chronic toxicity of ibogaine on
 cerebellar Purkinje cells in male
Fischer 344 rats. A behaviorally active dose of ibogaine (10 mg/kg, i.p.) was
 administered to a group of
six subjects every other day for 60 days while the control group received an
 equivalent volume of
saline (1 ml/kg). Estimates of Purkinje cell number were determined using the
 optical dissector/
fractionator technique. No significant differences in Purkinje cell number were
 observed between the
ibogaine

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