Seldane 
Author Message
 Seldane

Has anyone on this echo ever used Seldane for allergies before? What has been
your experience with it?  Is it a good one for long time use?  If you had
allergies would you stick with a G.P. kind of doctor or go to an allergy
specialist?  Thanks in advance...  +Mark O+

--  
Uucp: ...{gatech,ames,rutgers}!ncar!asuvax!stjhmc!120!175!Mark.Ochsankehl



Tue, 04 May 1993 20:26:43 GMT
 Seldane

        I've used Seldane and find it's only good for the watery
        eyes, scratchy throat type symptoms and doesn't do much
        for my nasal area.  Interesting since they say that trefenodene
        (sp?) is an H1 inhibitor but so is Actifed, yet Seldane doesn't
        make you sleepy.  By the way, every doctor that I've
        spoken with about this says that I should try taking (2)
        tablets instead of one.  This did make a difference but I
        still choose other antihistamines.
--
Taking action is a choice.
        Taking NO action is a choice as well.



Wed, 05 May 1993 03:53:56 GMT
 Seldane
I've used Seldane for a number of years.  It seems to work well for
me on a twice a day dosage.  I get little if any side effects.  About
my only complaint is that it can be difficult to decide when to stop
since my allergy symptoms rarely if ever break through.

For myself I went to an allergist primarily to have a series done as
it had been years and I wanted to know what I am allergic to.
Particularly I wanted to rule out allergies to our cats.  More recently
I've been seeing an ENT for the sinus problems.

Douglas S. Rand

Snail:      MITRE, Burlington Road, Bedford, MA
Disclaimer: MITRE might agree with me - then again...
Amateur Radio: KC1KJ



Wed, 05 May 1993 05:14:27 GMT
 Seldane

 >Has anyone on this echo ever used Seldane for allergies before?
 >What has been your experience with it?  Is it a good one for
 >long time use?  If you had allergies would you stick with a G.P.
 >kind of doctor or go to an allergy specialist?
 >Thanks in advance...  +Mark O+

Seldane is a very heavily advertised antihistamine.  While most
antihistamines cause significant sedation in the majority of
patients, Seldane was the first antihistamine not to be sedating.
Hism{*filter*}is a more recent, non-sedating antihistamine, and others
are on the way.  Unfortunately, both seldane and hism{*filter*}are
weak antihistamines.  I have tried them both, and I don't know
whether I can detect any effect.

If you have allergies, I would suggest a board-certified allergist.
Any doctor can, and many do, call themselves allergists.  Also, I
would STRONGLY recommend that you read an article entitled "Shot
Doctors" on page 96 of the February 1988 issue of "Consumer
Reports."




Thu, 06 May 1993 02:18:18 GMT
 Seldane
On <Nov 16 12:26> Mark Ochsankehl writes:

 MO> Has anyone on this echo ever used Seldane for allergies before? What has
 MO> been your experience with it?

It was good for emptying my wallet.

--  
Rick Ellis


BBS: 714 939-1041
--------------------------------------------------------------------------



Fri, 07 May 1993 05:37:43 GMT
 Seldane

Quote:

>Seldane was the first antihistamine not to be sedating.
>Hism{*filter*}is a more recent, non-sedating antihistamine, and others
>are on the way.  Unfortunately, both seldane and hism{*filter*}are
>weak antihistamines.  I have tried them both, and I don't know
>whether I can detect any effect.

Hism{*filter*}is generally considered one of the more potent and powerful
antihistamines.  It needs to be administered for several days (or a
large loading dose should be given for the first dose) to reach
appropriate {*filter*} levels, at which point a single 10mg dose a day is
sufficient.  It has an extremely long half-life.  These pharmacokinetic
characteristics make it most appropriate for chronic therapy--it
probably isn't the best antihistamine to use for treatment of
acute, short-lived exposure to allergens.

Loratadine is a new once-a-day antihistamine already in use in Canada.
It has a rapid onset of action and seems to be quite powerful, with no
sedative or drying side-effects.  I don't know what its FDA status is,
though I would imagine that it's in the pipeline.

When Seldane works well for people, it's a fine drug.  However, in
certain clinical studies it has appeared to be less effective than some
comparable benchmark antihistamines, and there have been anecdotal
reports such as your own that some people report that it doesn't work
well for them.  I don't think the variables which determine when
it will work well for which allergies in whom are well understood.
It's always worked fine for me.



Sat, 08 May 1993 02:44:35 GMT
 Seldane


Fri, 19 Jun 1992 00:00:00 GMT
 Seldane

Quote:

>Hism{*filter*}is generally considered one of the more potent and powerful
>antihistamines.  It needs to be administered for several days (or a
>large loading dose should be given for the first dose) to reach
>appropriate {*filter*} levels, at which point a single 10mg dose a day is
>sufficient.  It has an extremely long half-life.  These pharmacokinetic
>characteristics make it most appropriate for chronic therapy--it
>probably isn't the best antihistamine to use for treatment of
>acute, short-lived exposure to allergens.

After doing some followups and research, a local allergy expert (with
apparently some north-america wide reputation), Derek Wyse, observed
that the extremely long half-life is very true.  While the antihistamine
"effect" will wear off in a day or two, residual chemical traces can be
detected many MONTHS later.  He does NOT recommend any woman planning
a pregnancy in the next 6 months to use the stuff.  This is simply a case
of it lingers around and no research results are yet available on the effect
to fetouses (foetii :-?
In fact, when doing allergy testing, he insists you stay OFF the stuff for
a month to preferably 6 weeks before your appointment.

Quote:
>Loratadine is a new once-a-day antihistamine already in use in Canada.

  Sold under the tradename of: Claritin
 I like it.

Quote:
>It has a rapid onset of action and seems to be quite powerful, with no
>sedative or drying side-effects.  I don't know what its FDA status is,

   It seems quite fast in my opinion, and compared to my results with
years of Seldane, there is no apparent drying of the mouth.
    -ken
--
   - Ken{*filter*}s, Software Development Group, UofWaterloo, Canada [43.47N 80.52W]




Sat, 08 May 1993 09:49:09 GMT
 Seldane


Fri, 19 Jun 1992 00:00:00 GMT
 Seldane

Quote:
> Has anyone on this echo ever used Seldane for allergies before? What has been
> your experience with it?  Is it a good one for long time use?  If you had
> allergies would you stick with a G.P. kind of doctor or go to an allergy
> specialist?  Thanks in advance...

I've used Seldane.  Works pretty good but makes me sleepy.  It's not supposed
to make ANYONE sleepy but I'm weird!  
Definitely go to an allergist.  My GP mucked around with my asthma until I was
acute and ended up in the hospital.  At the present I am on prednisone (10 mg a
day), organidon, an antibiotic (to keep me from going into bronchitis), Intal
inhaler, Ventolin Rotocap inhaler.  Oh, yes, I also get allergy shots every
week.  I feel like a walking pill bottle and my asthma is still not under
control at all since I can't go off the steroid.  I've tried but 10 mg is the
minimal doseage I can take.  I also can not take any theophylin due to extreme
reactions to anything that resembles caffeine.  Sigh.....


Sun, 09 May 1993 01:27:37 GMT
 Seldane
My Son used Hismanel (similar to Seldane) for about a year.  Before
using, his nose ran so
much his teachers at school complained of class interuption by his
blowing his nose all the time.
NOTHING the doctors tried worked.  But, Hismanel  (Sp?) completely
stopped his nose drainage.
Now he has been able to stop using it, which I do not understand.  One
problem is that it made
him want to eat more and is now overweight!

Ray T.



Sun, 09 May 1993 06:48:55 GMT
 Seldane

Quote:
> Has anyone on this echo ever used Seldane for allergies before? What has been
> your experience with it?  Is it a good one for long time use?  If you had
> allergies would you stick with a G.P. kind of doctor or go to an allergy
> specialist?  Thanks in advance...  +Mark O+

My experience with Seldane, the anti-histamime that isn't supposed to
make you drowsy, is that it made me incredibly drowsy.  That's not
true for everyone, though I have heard it from a few others.

It's also supposed to last 12 hours (2 per day).  Go to your
doctor, it's worth trying.
--



Sun, 09 May 1993 16:40:26 GMT
 Seldane

 MO> Has anyone on this echo ever used Seldane for allergies before?

I tried it and, though it didn't make me sleepy, it also did
nothing whatsoever to my nasal mucosa.
HISMANOL, on the other hand, works quite well, and is non-
sedating.  
A less expensive, probably more reliable regimen is to use Atarax
(a plain old antihistamine whose sedating effects last for 7-8
hours, while the antihistaminic effects last more like 24 hours.  
You take about 75-100 mg near bedtime, get a good night's sleep
and keep freer of allergy symptoms through the day.

 MO> If you had allergies would you stick with a
 MO> G.P. kind of doctor or go to an allergy specialist?

     Depends on the GP.  Actually, there are few GP's out there,
and you are probably talking about Family Practitioners (who go
through a 3-year residency after med school like the internists or
pediatricians).  If that doc is good at treating allergies, you
are better off going to him/her than to an allergist.

--  
Uucp: ...{gatech,ames,rutgers}!ncar!asuvax!stjhmc!212!102.0!Phil.Thwing



Sun, 09 May 1993 21:57:01 GMT
 Seldane


Fri, 19 Jun 1992 00:00:00 GMT
 Seldane

I heard a month or two ago that Seldane was going to be on the OTC
list soon.  Has this happened yet?  (Can I start getting it other than when
friends go to Canada? :-)
--

Systems Manager - University of Houston Dept. of Mathematics - (713) 749-2120

Skate UNIX(r)



Mon, 10 May 1993 09:03:22 GMT
 
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