STATIN THERAPY COULD REDUCE CALCIUM DEPOSITS IN ARTERIES
Statin therapy could reduce calcium deposits in arteries: Study
ANI
Tuesday, June 10, 2003
Hong Kong - Lifestyle changes combined with statin
therapy can reduce calcium deposits in the heart arteries
of patients at risk of coronary artery disease who still
have no symptoms, according to a new study.
"The rate of progression of calcium scores was less.
Statin therapy, in addition to lifestyle modification,
induced a 32 per cent rate of reduction in the coronary
calcium scores in asymptomatic patients", said Victor K
Goh, consultant cardiologist at the Electron Beam Centre,
Matilda International Hospital in Hong Kong.
This study shows that early detection and treatment can
prevent coronary artery disease from progressing and, in
some cases, allows the disease to regress.
The EBT scan detects levels of calcium deposited on
cholesterol plaques in the arteries, which can
deteriorate and lead to blockages requiring
revascularization procedures such as angioplasty,
stenting or bypass surgery. A calcium score is then
ascertained by the amount of calcium discovered in the
arteries.
"If the patients have risk factors for coronary artery
disease and by electron beam tomography are found to have
coronary disease, then adopting a healthy lifestyle (a
diet and exercise programme) and being placed on statins
can do a lot to alleviate the problem", Goh noted.
The study involved 102 patients who underwent EBT in
1990-1992 then again 12 years later. All the participants
were at high risk for coronary artery disease and were
given physical examinations and calcium scores. Then they
were placed on statins and lifestyle modification
including diet, exercise and weight control.
The team found that almost one-third of the enrolled
patients taking statins and adopting lifestyle changes
had reduced calcification scores. "These patients did not
want stenting or surgical intervention, even if they were
found to have significant blockages. But treatment with
statins and aggressive life-style changes helped them
avoid revascularization procedures", Goh added.
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