ASH Highlights Bulletin Sample & Index 
Author Message
 ASH Highlights Bulletin Sample & Index

A daily summary of selected presentations made at the tenth
Scientific Meeting of the American Society of Hypertension, New
York, NY.

-------------------------------------------------------------
Special thanks to Donald Vidt, MD, Senior Physician,  Department of
Hypertension/Nephrology, Cleveland Clinic Foundation and Lionel
Mailloux, MD, Senior Attending, Div. Nephrology, North Shore Univ.
Hospital-Cornell University Medical College, Manhasset, NY,  for serving
as Guest Editors of ASH-EHLB. The ASH-EHLB is made possible through an
educational grant provided by Marion Merrell Dow, Inc. with editorial
support by Pharmaceutical Information Associates, Ltd.

Copyright 1995, PIA Ltd.
-------------------------------------------------------------

ANNOUNCING ASH-EHLB ARCHIVES
A New Mailing List for the Dissemination of the HighLights Bulletin of the
Tenth Scientific Meeting of the American Society of Hypertension

=================
ASH-EHLB is an innovate service provided by the American Society of
Hypertension to disseminate key information from the Tenth Scientific
Meeting of the Society, held on May 17 through May 20, 1995. Through this
mailing list, a broad audience of health professionals followed the
proceedings on a daily basis via E-mail delivery!

CONTENTS
=========
SAMPLE (Bulletin_1.1)
COMPLETE CONTENTS LISTING
HOW TO ORDER FROM THE ARCHIVES

SAMPLE
=======
A sample of the first bulletin follows:

ASH Electronic Highlights Bulletin #1: May 17, 1995
05/17/95
------------------------------------------------------------
BULLETIN_1.1
PART 1 of 6
------------------------------------------------------------
Special thanks to Donald Vidt, MD, Senior Physician,  Department of
Hypertension/Nephrology, Cleveland Clinic Foundation, for serving as Guest
Editor of this ASH-EHLB issue. The ASH-EHLB is made possible through an
educational grant provided by Marion Merrell Dow, Inc. with editorial
support by Pharmaceutical Information Associates, Ltd. Copyright 1995, PIA
Ltd.


------------------------------------------------------------

ash_2.doc
HYPERTENSION MANAGEMENT in PATIENTS WITH DIVERSE PRESENTATIONS
Wednesday, May 17, 1995
Speakers: James Sowers, MD; Marc Pfeffer, MD, PhD; Janice
Douglas, MD; John Flack, MD, MPH.

There is an increasing recognition that the optimal management of
hypertension is based on a clear understanding of the diverse
pathophysiologic conditions underlying various hypertensive patients
groups.

For example, an increasing body of evidence supports the relationship
between obesity, insulin resistance/hyperinsulinemia, type II diabetes
mellitus and hypertension in women. The ongoing CARDIA study (Coronary
Artery Disease Risk Factor Study  has been underway for 6 years and is
assessing equal numbers of African-Americans and whites of both genders.
In 4576 patients evaluated so far, a single elevated fasting insulin level
was positively correlated with increasing systolic and diastolic {*filter*}
pressure, total and low density LDL cholesterol, and apoprotein B;
negative correlations were seen between insulin and HDL cholesterol,
apoprotein A-1 and heavy physical activity. African-American women had the
highest insulin levels.  While the mechanisms that link these factors to
hypertension are not clear, interest focuses on the role of insulin
resistance. Women with central obesity have significantly higher insulin
and glucose concentrations after an {*filter*}GT. than women with gluteofem{*filter*}
obesity ; this may be due to the observation that abdominal adipocytes
have fewer insulin receptors, are less insulin responsive, and have
greater sensitivity to lipolytic hormones than adipocytes found in the
gluteofem{*filter*}area.

During the acute phase of an MI, variable degrees of monocyte necrosis
occur and arterial {*filter*} pressure tends to fall. Therefore, in survivors
of MI, arterial pressure may not portend the same prognosis as in patients
without MI. Nevertheless, there is a consistent finding among studies of
postinfarct patients that even a history of hypertension carries a higher
risk of adverse cardiovascular events. Results from 837 patients enrolled
in the Survival and Ventricular Enlargement study have similarly found
that these individuals maintain physiologic mechanisms that contribute to
cardiovascular decompensation even in the absence of continued overt high
{*filter*} pressure, indicating the need for continued monitoring and therapy
in these patients.

Among the best studied of the hypertensive subgroups are African-American
patients, particularly those with salt-sensitive hypertension. Although
genetic factors predispose these patients to hypertension, environmental
factors such as access to health care, socioeconomic status, stress, diet,
and obesity account for some of the racial differences in hypertension
seen worldwide. Fifty to 70% of hypertensive African-Americans have an
enhanced capacity for renal salt resorprtion compared to 27% of the
hypertensive white population. Renal salt retention leads to an expanded
plasma volume with inhibition of  the RAS system. Intracellular sodium
concentrations are higher in hypertensive than normotensive blacks and the
increased sodium concentration is positively correlated with increasing
{*filter*} pressure in blacks. Several physiologic mechanisms underly
electrolyte- mediated hypertension, including alterations in the sodium/H
exchanger mechanism, the lithium/sodium pump, the sodium/potassium pump,
and the sodium/potassium cotransporter mechanism. Ethnic differences in
the activity of these cellular ion pumps have been observed not only in
blacks but also in Asians and those of Jewish descent.  

Because a variety of diverse factors underly hypertension in special
populations, therapy must be tailored specifically for each patient.
Recommendations of JNC-V indicate that {*filter*} pressures above 130/85 mmHg
should be considered for treatment. Such recommendations stem from
findings that even high normal {*filter*} pressure (approaching the upper JNC-V
limit) has been associated with the development of hypertension and LVH
over a 7-year period particularly in blacks. Drug therapies with
diuretics, beta-blockers and alpha blockers can be effective in selected
populations but may be limited by adverse events and alterations in serum
lipid values. Calcium antagonists, in particular the longer-acting agents
such as verapamil, diltiazem, nifedipine, and isradipine are highly
effective, but should be used cautiously in the elderly and those with
CHF. ACE inhibitors are particularly useful in type-I diabetics at risk
for hypertension, offering a renoprotective effect and possible benefits
post MI. Drug strategies should be chosen to maximize compliance, and to
minimize loss of {*filter*} pressure control when doses are missed.

COMPLETE CONTENTS LISTING
=========================

TITLE                                                   FILENAME
=======================================                 ============
AMERICAN SOCIETY OF HYPERTENSION POSTER SESSION.........BULLETIN_4.6
AMERICAN SOCIETY OF HYPERTENSION POSTER SESSION.........BULLETIN_3.7
AMERICAN SOCIETY OF HYPERTENSION POSTER SESSION.........BULLETIN_2.5
ANGIOTENSIN ANTAGONISTS AND RENIN INHIBITORS:
   A REAL STEP FORWARD..................................BULLETIN_4.4
ANGIOTENSIN II: IMPACT OF BASIC SCIENCES ON
   CLINICAL PRACTICE....................................BULLETIN_1.5
CLINICAL HYPERTENSION: From Clinical Trials to
   Clinical Practice....................................BULLETIN_5.4
CLINICAL TRIALS: NEW FINDINGS FROM COMPLETED
   STUDIES AND FUTURE DIRECTIONS........................BULLETIN_5.3
DEBATE: DIURETICS - THE QUESTIONS CONTINUE..............BULLETIN_3.4
DEBATE: SHOULD DIHYDROPYRIDINES BE USED FOR
   FIRST-LINE TREATMENT OF HYPERTENSION?................BULLETIN_3.5
DISCUSSION OF HOME AMBULATORY {*filter*} PRESSURE
   MONITORING...........................................BULLETIN_3.1
EFFECT OF ACE INHIBITION ON PROGRESSION OF
   CARDIOVASCULAR DISEASES..............................BULLETIN_1.3
HOW LOW SHOULD {*filter*} PRESSURE BE?.......................BULLETIN_5.5
HYPERTENSION (ASH/GOVERNMENT/ACADEMIA/INDUSTRY
   SYMPOSIUM)...........................................BULLETIN_3.8
HYPERTENSION IN SPECIAL POPULATIONS.....................BULLETIN_1.4
HYPERTENSION MANAGEMENT in PATIENTS WITH DIVERSE
   PRESENTATIONS........................................BULLETIN_1.1
METABOLIC ISSUES AND TREATMENT OF HYPERTENSION..........BULLETIN_2.6
OUTCOMES, HYPERTENSIVE DISEASE, AND ITS TREATMENT:
   A Prospective Study of Disease Progression in
   Patients with Atheroscl{*filter*} Renal Artery Stenosis..BULLETIN_4.2
OUTCOMES, HYPERTENSIVE DISEASE, AND ITS TREATMENT:
   Isolated Systolic Hypertension (ISH): The Most
   Powerful Risk Factor of Stroke and MI................BULLETIN_4.3
OUTCOMES, HYPERTENSIVE DISEASE, AND ITS TREATMENT:
   Urinary Albumin Excretion: A Stronger Predictor
   of Cardiovascular Risk than {*filter*} Pressure and
   Serum Cholesterol....................................BULLETIN_4.1
PATIENT EVALUATION: Ambulatory Monitoring of {*filter*}
   Pressure in Evaluating Hypertensive Patients.........BULLETIN_5.2
PATIENT EVALUATION: Is the Recommended Workup
   Adequate?............................................BULLETIN_5.1
SOCIOECONOMIC DETERMINANTS OF HYPERTENSION AND ITS
   CONTROL: STRESS AND HYPERTENSION.....................BULLETIN_2.7
SOCIOECONOMIC DETERMINANTS OF HYPERTENSION AND ITS
   CONTROL: Data from the Third National Health
   and Nutrition Examination Survey.....................BULLETIN_3.2
SOCIOECONOMIC DETERMINANTS OF HYPERTENSION AND ITS
   CONTROL: Inner City Minorities and Hypertension......BULLETIN_3.3
SUNRISE SEMINAR SERIES INDIVIDUALIZATION OF
   TREATMENT FOR HYPERTENSION in 1995...................BULLETIN_2.1
SUNRISE SEMINAR SERIES MANAGEMENT OF HYPERTENSION
   IN MINORITIES: AFRICAN-AMERICANS, HISPANICS..........BULLETIN_3.6
SUNRISE SEMINAR SERIES: COMPLIANCE TO THERAPY...........BULLETIN_4.5
THE EMERGING ROLE OF CHRONOTHERAPEUTICS IN MANAGING
   HYPERTENSION.........................................BULLETIN_1.6
THE PATHOBIOLOGY OF ATHEROSCLEROSIS: From Fatty
   Streak to Myocardial Infarction......................BULLETIN_2.2
THE PATHOBIOLOGY OF ATHEROSCLEROSIS: Modification
   of LDL Structure in Relation to Atherosclerosis......BULLETIN_2.3
THE ROLE OF SOCIOECONOMIC STATUS IN HYPERTENSION........BULLETIN_2.4
UNRESOLVED ISSUES IN THE TREATMENT OF HYPERTENSION......BULLETIN_1.2
--------------------------------------------------------------------

HOW TO ORDER EHLB ARCHIVES
==========================
WWW> The ASH-EHLB Archives are available to anyone with access to the
World-Wide Web. Point your browser to

              http://www.***.com/

E-MAIL> The ASH-EHLB Archives are also available via E-mail:

STEP 1: Subscribe to ASH-EHLB
-----------------------------

the body:

          SUBSCRIBE ASH-EHLB yourname

(Substitute your first and last name for "yourname"; ie,
SUBSCRIBE ASH-EHLB John Doe). The rest is handled
automatically by the list software.

Alternatively, you may send an e-mail message to

the body:

          SUBSCRIBE yourname

STEP 2: Send a command to the Archives to receive the desired bulletin
section(s):
----------------------------------
NOTE: You must subscribe to ASH-EHLB first; see STEP 1.
To receive the desired section of the bulletin, send the command:

     SEND FILENAME

in the body of an Email message addressed to:


Substitute the appropriate filename for FILENAME.
For example to receive BULLETIN_1.1 use the command

     SEND BULLETIN_1.1

To receive all sections of the bulletin use the command

     SEND BULLETIN_1

--
John Mack
----------------------------------------------
John Mack       1-215-949-0490
Pharmaceutical Information Associates, Ltd.
2761 Trenton Road, Levittown, PA 19056 USA
Creators of PharmInfoNet, a Web site devoted to pharmaceutical information.
URL: http://www.***.com/




-----------------------------------------------



Tue, 11 Nov 1997 03:00:00 GMT
 
 [ 1 post ] 

 Relevant Pages 

1. ASH Highlights Bulletin Sample & Index

2. NEW> ASH Electronic HighLights Bulletin

3. NEW> ASH Electronic HighLights Bulletin

4. ASH Highlights Bulletin to be Peer-reviewed

5. NEW> ASH Electronic HighLights Bulletin

6. PME FYI: ASH Electronic HighLights Bulletin

7. NEW> ASH Electronic HighLights Bulletin

8. ASH Highlights Bulletin to be Peer-reviewed

9. Free Samples-Health & Nutrition Survey-Free Samples

10. norwich bulletin : Current News. norwich bulletin,the norwich bulletin,justin pepper norwich bulletin,norwich bulletin norwich connecticut,obituaries norwich bulletin

11. sample resumes : Final News. sample teacher resumes,sample carpenter resumes,sample resumes accountant,sample construction worker resumes,sample teaching resumes

12. Nuclear Imaging Technologists - submit your resume to our bulletin board - index.htm (0/1)


 
Powered by phpBB® Forum Software