Physiological Weight Gain Issues 
Author Message
 Physiological Weight Gain Issues

[ This note got a little longer than I had intended...]

A couple of months ago, Craig Werner posted an article regarding
Nutrasweet and increased appetite.  If I remember correctly, he stated
that it was the sweet taste in the mouth that led to insulin being
released; without any sugar being digested, this would lead to lower
{*filter*} sugar, and then increased appetite.

Does this jive with other people's understanding of digestion?  I would
have guessed that it was the glucose in the {*filter*} that would have led
to the insulin being released, not taste.

I'm curious because I have been reading a book which suggests a link between
obesity and inefficient use of insulin (leading to overproduction of insulin
leading to increased appetite as well as a resistance to using the body's
own fat stores) and I wonder whether it is true that drinking, say, Diet Coke
without">food would lead to insulin being released.

Any comments would be appreciated.  Note that this book prescribes a
high-protein, low-fat and carb (under 40 grams a day) diet to keep the dieter
in mild ketosis.  My understanding is that eating the protein foods spares
the muscle because there are all these amino acids floating around in the
{*filter*} and is happy to use the fat for other energy needs.

Now I realize that most medical people advocate a small weight loss per week,
instead of the 2-3 you can take off with these types of programs (Optifast
being a typical one).  I also wonder about the gallstone factor regarding
losing weight too quickly.  And I also realize that there are some issues
regarding changing behaviors in order to keep the weight off.

But I wonder if the appetite suppressant feature of ketosis doesn't outweigh
some of these issues if the dieter has a lot to lose.  

If all you have to say is "eat less and exercise more", please don't bother
to respond.  I was watching Oprah last week, and she had on 5 guests who were
unable to maintain a low weight.  I suspect that there is a physiological
reason (such as inefficient insulin, or need for serotonin, etc.) in addition
to a psychological reason for inability to keep the weight off.  

For example, is there a link between sugar and weight gain?  And again, I don't
just mean, yeah if she eats a ton of Twinkies, she'll get fat.  Could there
possibly be some chemical chain reaction in some groups of people that causes
them to crave carbohydrates when they eat sugar?  I have always maintained
that people wouldn't overeat if it didn't serve a purpose.  I believe that
people who do this get a major sedative effect from overeating.  But the
problem is that, for them, it is like drinking or drug abuse.  It takes more
and more of the quantity of abusive substance to receive the same "high"; in
the meantime, they start packing on the pounds from their destructive habit.

I'm not a big 12-step fan, but there is now a group called">food {*filter*}s Anon.
who abstain from sugar *and* wheat products, claiming that this allows them
to be free from the physiological problems of {*filter*}ion, leaving them able
to cope with their psychological problems.

Anyways, I am starting to learn more about what types of physiological
explanations might contribute to weight gain.  Reminder, I *already* know about
the "eat less/exercise more" ideas.  Any additional pointers or info would be
greatly appreciated.


Beth Mazur                          "Nobody gets a lifetime rehearsal; as

...!uunet!inmet!mazur                                  -- The Indigo Girls

Sat, 01 May 1993 01:53:00 GMT
 Physiological Weight Gain Issues


...stuff deleted>
>Now I realize that most medical people advocate a small weight loss per week,
>instead of the 2-3 you can take off with these types of programs (Optifast
>being a typical one).  I also wonder about the gallstone factor regarding
>losing weight too quickly.  And I also realize that there are some issues
>regarding changing behaviors in order to keep the weight off.

Yes, there are many issues involved in loosing weight, but this
principle should remain cardinal in *any* dieter's mind, regardless of
the techniques or diets or exercise regimines used;
The body *regulates* itself around a set-point weight, and will
adjust it's metabolism to do so (i.e., if you consume less calories,
you will burn less).
This invidious set-point is more likely to move *upwards* if
you loose weight *rapidly*. Thus, if you loose 10lbs in 3 months,
chances are good (assuming you had the right diet and exercise, build
more muscle, etc) that your body will be able to regulate around this
new weight. If you loose that same 10lbs in 1 month, however, your body
is more likely to try to regulate around a set-point which is *higher*
than that with which you started. That's why extreme and rapid
weight loss is often followed by rapid regaining to an even *higher*



Sun, 02 May 1993 00:03:12 GMT
 Physiological Weight Gain Issues

>>The body *regulates* itself around a set-point weight, and will
>>adjust it's metabolism to do so (i.e., if you consume less calories,
>>you will burn less).

>Clinical evidence?  Please, ramdomly selected groups only!

...stuff deleted about self-selection....

>Please refer to my ADIPOSTY 101 posting some months back for details.

You are quite right about many people self-selecting into rapid
weight-loss, thereby possibly confounding the results with a priori
biological differences. My post was based on rat (keesey & powell?) and
primate studies which did randomly assign. I don't know the human
clinical literature well enough offhand to respond to your reasonable
request---and I won't have the time this week to search my data-bases.
But although I cannot confirm that none exist, I could well imagine the
difficulty of conducting such truly unconfounded human studies.
On that basis alone, plus the propensity for *most* medical/clinical
research to be imperfect on many counts, such cites may indeed be rare.

Still, I do believe there is reasonable convergent evidence that the heuristic
to loose weight slowly (and to maintain or increase the muscle-to-fat ratio) is
at least prudent, facilitates adaptive behavi{*filter*}change and nutrition,
and is not *contraindicated*. I would be especially interested in
any information which challenges the last assertion: it would be quite
another matter if it has been found that slower weight loss somehow
exacerbates the regulation problem.


Thu, 06 May 1993 01:51:25 GMT
 Physiological Weight Gain Issues
Rheumatoid Arthritis is a disease of the immune system.  Does any know if
having RA affects susceptability to AIDS?

Arnold Chamove
Massey University Psychology
Palmerston North, New Zealand

Mon, 10 May 1993 10:55:08 GMT
 [ 4 post ] 

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