
Risk of lowering cholesterol with diet and drugs.
Quote:
> I recently read a Los Angeles Times article on the risk of lowering
>cholesterol with diet and {*filter*}. It says that there is a growing body
>of evidence that lowering cholesterol via {*filter*} and diet may indirectly
>raise the the risk of certain types of {*filter*} death by producing person
>-ality changes. These include anger, irritability, and increased risk
>taking. It also says that lowering cholesterol in monkeys reduces levels
>of the neurotransmitter serotonin, and that low levels of serotonin in
>humans have been linked to an increased risk of aggressive behavior and
>suicide.
> Has anyone else heard of this and do you know of any specific studies?
>The article didn`t give any specific information about the studies.
The hypothesized link between serotonin and and {*filter*} behavior and
suicide is mostly based on studies of the principal metabolite of
serontonin in the cerebrospinal fluid. For example, suicide victims
were found to have low serotonin metabolite (5 HTIAA); suicide victims
dying {*filter*} deaths (e.g., gunshot) had lower levels than non{*filter*}
deaths (e.g., overdose). Good reference: Asberg M, Schalling D, et al:
Psychobiology of Suicide, Impulsivity, and Related Phenomena. In
Meltzer HY: Psychopharmacology: The Third Generation of Progress, New York,
Raven Press, 1987.
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