A year or so ago, there was big news about the use of inhaled DNase to
thin out the mucous in the lungs of cystic fibrosis patients. Initial
results were promising and so clinical trials had commenced (I'm not
sure where).

Recently I was talking to an MD from the Alberta Sick Childrens
Hospital in Calgary. He said that the introduction of DNase therapy
into general use had been delayed because some researchers had concerns
that the breakdown products of Pseudomonas were more harmful than the
Pseudomonas itself.

Does anyone know the status of the clinical trials, the schedule for
introduction of DNase into widespread use or anything about the
reference to Pseudomonas. I have two 18 month old twin girls with CF,
so naturally I'm a little concerned.

Thanks!

John Elton McFee                   ---   Standard disclaimer.
Threat Detection Group             ---   I speak for the trees