GOING BEYOND ANTIBIOTICS: THE ABILITY OF PATHOGENS TO MUTATE AND
HOST-DEFENSE SYSTEMS
Dear Colleagues and Interested Others;
There are many of us that realize that pathogens come in many different
forms, are able to mutate and vary in their ability to multiply and
proliferate. There relative pathogenicity and virulence may relate directly
to the status of the person's host-defense system. There are efforts
presently underway to solve the problem of ever increasing
antibiotic-resistant bacteria and other pathogens. Developing another
antibiotic will only work until the pathogen mutates to get around the the
new antibiotic. The strategy to look only for new antibiotics is
palliative, only. This calls for an effort to optimize host-defense
systems through diet, nutrition, lifestyle, environmental and other factors
It is interesting to note that the person who wrote in about having an
antibiotic resistant bacterial condition said nothing about the status of
his host defenses. What is the status of his immune system? What laboratory
work has been done to measure his immune capabilities to mount a defense?
THERE IS THE SEED (PATHOGEN) AND THERE IS THE SOIL (HOST DEFENSE SYSTEMS).
Detailed quantitative organic acid analysis to determine plasma glutathione
and to determine specific analyte, solute and metabolite patterns
(ORTHOMOLECULAR ASSESSMENT) may be important in addition to other standard
tests to determine immune status.
NEGATIVE FACTORS;Elevated levels of toxic metals, pestcide exposure, cooking.net">food
allergy, elevated {*filter*} glucose or {*filter*} lipids, heavy exercise, excessive
or deficient caloric intake, mercury amalgams, lawn chemical exposure and
other factors.
POSITIVE FACTORS; Selenium supplements, supplemental sulphur based amino
acids for precursor loading to raise plasma glutathione, anitioxidant
supplementation (raise plasma ascorbate), moderate exercise, massage,
laughter and neurocognitive states, gastrointestinal health and other
factors.
I use a PATIENT-CENTERED APPROACH, with EXTENSIVE PATIENT-DATABASING,
including referral for lab work to help me develop A COMPREHENSIVE STRATEGY
rather then to focus only on how many or what new, different antibiotics
can be used on this patient. If past pathogens in this patient have
mutated in past antibiotic applications, it is highly likely that new
antibiotics for this patient will result in new, mutated and virulent
strains of the slightly different and altered past pathogen. Many
pathogens may become "STEALTH PATHOGENS" able to pass through and below the
body's radar system. SEE
Mattman, LH. CELL WALL DEFICIENT FORMSP; STEALTH PATHOGENS, 2ND ED., Crc
Press, Boca Raton, Florida, 1992
A SOCIALISTIC, PUBLIC HEALTH MODEL approach to anti-biotic resistant
pathogen strains will cause the clinician to look only at the infecting
agent, its pathogenicity, virulence and accepted pathophysiology separate
from the patient, while a PATIENT-CENTERED APPROACH looks at what is
happening inside of the patient. WHY NOT USE BOTH?
From the cutting edge,
(718) 460-3966, American Academy of Anti-Aging Medicine, International
Association of Biomedical Gerontology, National Academy of Elder Law
Attorneys, American Aging Association, Life Extension Foundation, American
Academy of Clinical Gerontology, Trained: Psychoanalysis, Certified:
Mediation & Counseling, Certified: Functional Assessments & Interventions,
Art. 81, NY MHL, Certified: Interdisciplinary Geriatrics: Geriatric
Assessment, Columbia University--NY Geriatric Education Center