
Iodine / bronchial asthma
Int Immunopharmacol. 2005 Apr;5(4):805-10. Related Articles, Links
Effect of lecithin-bound iodine on the patients with bronchial asthma.
Kawano Y, Saeki T, Noma T.
Department of Pediatrics, Kitasato University, Japan.
Lecithin-bound iodine (LBI), which has been reported to be a potential
candidate for one of the therapeutic modalities for children with
bronchial asthma based on the in-vitro study, was also found to be
effective in relieving the symptoms of patients with childhood asthma.
In addition to the in-vitro effect of downregulation and upregulation
of interleukin-4 (IL-4) and interferon-gamma (IFN-gamma), respectively,
the clinical effect of LBI was highlighted through the concomitant
upregulation of IFN-gamma production by the patients' lymphocytes,
which were treated with LBI for 8 weeks. Therefore, LBI may reduce the
signs of bronchial asthma by upregulating the synthesis of IFN-gamma
that is a representative Th1 cytokine.
PMID: 15710348 [PubMed - in process]
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